Games are a powerful educational tool, as confirmed by philosophers and pedagogists who highlight its importance in developing skills such as problem-solving and creativity. Chemistry, often seen as an abstract discipline, can benefit from a playful approach. Giochi della Chimica, organized by Società Chimica Italiana since 1984, have been extended to lower secondary schools with the Giochi di Avogadro. The first edition, held in the 2023-2024 school year, saw the participation of 1700 students from all over Italy. The results show a high level of engagement, with positive feedback from both students and teachers, confirming the effectiveness of this approach in stimulating active learning.